2015 ESC/ERS Guidelines

opsumithcp.com Review:

OPSUMIT® (macitentan) HCP PAH Treatment Information - Learn more about OPSUMIT® (macitentan), an endothelin receptor antagonist, including PAH (WHO Group 1) disease education, and more.

http://opsumithcp.com/important-safety-information Important Safety Information for OPSUMIT® (macitentan) - Find important safety information for OPSUMIT® (macitentan) including the Boxed Warning for embryo-fetal toxicity.

http://opsumithcp.com/seraphin-study-overview OPSUMIT® (macitentan) SERAPHIN Clinical Trial Results - Find SERAPHIN clinical trial results & patient subgroups for OPSUMIT® (macitentan) in pulmonary arterial hypertension (WHO Group 1) treatment.

http://opsumithcp.com/seraphin-baseline-characteristics SERAPHIN Clinical Trial Baseline Characteristics - Find SERAPHIN clinical trial baseline characteristics for OPSUMIT® (macitentan) in pulmonary arterial hypertension (WHO Group 1).

http://opsumithcp.com/efficacy-overview Efficacy of OPSUMIT® (macitentan) in PAH Treatment - Learn more about the efficacy & safety of OPSUMIT® (macitentan) in PAH (WHO Group 1) treatment.

http://opsumithcp.com/delay-in-disease-progression Effect of OPSUMIT® (macitentan) on PAH Progression - Learn more about the PAH (WHO Group 1) progression endpoint in the SERAPHIN clinical trial for OPSUMIT® (macitentan)

http://opsumithcp.com/delay-in-disease-progression-monotherapy-combo-therapy OPSUMIT® (macitentan) Monotherapy & Combination Therapy - Find OPSUMIT® (macitentan) monotherapy and combination therapy subgroup analyses.

http://opsumithcp.com/reduced-risk-of-PAH-related-hospitalization Effect of OPSUMIT® (macitentan) on PAH Related Hospitalization - Learn more about the PAH (WHO Group 1) related hospitalization endpoint in the SERAPHIN clinical trial for OPSUMIT® (macitentan).

http://opsumithcp.com/short-term-symptomatic-and-functional-endpoints OPSUMIT® (macitentan) Secondary & Exploratory Endpoints - Learn more about the OPSUMIT® (macitentan) short-term symptomatic and functional endpoints in PAH (WHO Group 1) patients.

http://opsumithcp.com/adverse-reactions Adverse Reactions of OPSUMIT® (macitentan) - Learn more about the adverse reactions of OPSUMIT® (macitentan) from the SERAPHIN study and postmarketing experience for OPSUMIT.

http://opsumithcp.com/mechanism-of-action Proposed Mechanism of Action for OPSUMIT® (macitentan) - Review how the mechanism of action for OPSUMIT® (macitentan) works on the endothelin pathway, and is the result of an extensive drug discovery program.

http://opsumithcp.com/prescribing Prescribing Overview for OPSUMIT® (macitentan) - Find prescribing details for OPSUMIT® (macitentan) including PAH (WHO Group 1) patient access and OPSUMIT® dosing and administration details.

http://opsumithcp.com/dosing-and-administration Dosing and Administration for OPSUMIT® (macitentan) - Find information about the dosing and administration of OPSUMIT® (macitentan) for PAH (WHO Group 1).

http://opsumithcp.com/opsumit-voucher-program OPSUMIT® (macitentan) Voucher Program - Learn how your PAH (WHO Group 1) patients can receive a 30-day free supply of OPSUMIT® (macitentan) through the OPSUMIT® Voucher Program.

http://opsumithcp.com/support-and-services-overview OPSUMIT® (macitentan) Support and Services Overview - View patient support programs like Actelion Pathways®, OPSUMIT P.L.U.S. (Patient Learning, Understanding, and Support)™ Program and OPSUMIT REMS Program.

http://opsumithcp.com/actelion-pathways Actelion Pathways OPSUMIT® (macitentan) Patient Support - Learn how Actelion Pathways® offers patient support for OPSUMIT® (macitentan) PAH (WHO Group 1) treatment through PAH education and resources.

http://opsumithcp.com/opsumit-plus-program The OPSUMIT (macitentan) P.L.U.S.® Program - Learn about patient support for OPSUMIT® (macitentan) with the OPSUMIT P.L.U.S. (Patient Learning, Understanding, and Support)® Program.

http://opsumithcp.com/disease-education Pulmonary Arterial Hypertension Disease Overview - Get information about PAH (WHO Group 1) diagnosis, signs and symptoms, disease progression, and disease classification.

http://opsumithcp.com/PAH-overview About Pulmonary Arterial Hypertension - Learn more about PAH (WHO Group 1), including hemodynamics, clinical parameters, pathological events, and the pulmonary vasculature.

http://opsumithcp.com/disease-progression-in-PAH PAH Disease Progression - Learn more about the rapidly progressive nature of PAH (WHO Group 1) and the 3 pathways involved in symptomatology and disease progression.

http://opsumithcp.com/diagnosing-PAH Pulmonary Arterial Hypertension Diagnosis - Review key screening & exclusionary diagnostic tests used for diagnosing PAH (WHO Group 1).

http://opsumithcp.com/classifying-PAH PAH Classification within WHO Group 1 - Review the clinical classification for pulmonary arterial hypertension within World Health Organization Group 1.

http://opsumithcp.com/signs-and-symptoms-of-PAH Pulmonary Arterial Hypertension Symptoms - Find the signs and symptoms of pulmonary arterial hypertension (WHO Group 1), including physical signs and top common symptoms.

http://opsumithcp.com/esc-ers-guidelines 2015 ESC/ERS Guidelines - Review pulmonary hypertension recommendations for Phase III PAH (WHO Group 1) clinical trials from the 4th and 5th World Symposia.

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